佰乐博生物蛋白抗体推荐Research Grade Tanfanercept (DHB94439)特那西普
一、中文名称:Research Grade Tanfanercept (DHB94439),研究级Tanfanercept类似物研究级特那西普
二、产品描述
特那西普Tanfanercept (HL036337) 是一种 TNF-α receptor 的融合蛋白,靶向 TNF-α。特那西普Tanfanercept 在干眼症 (DE) 小鼠模型中可有效改善角膜糜烂。
三、产品详情
名称:Research Grade Tanfanercept (DHB94439)
别名:Anti-TNF-alpha protein, HBM-9036, HL 036, HL-036, HL-036337, HL-189, TNF-alpha blocker
货号:DHB94439
表达系统:Mammalian Cells
种属反应性:Human
同种型:Tumor Necrosis Factor (TNF) binding protein variant 1 (tbp-1)
克隆类型:Monoclonal
靶标:TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1
浓度:1 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS-PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
Accession号:P01375
克隆号:Tanfanercept
应用:Research Grade Biosimilar
状态:Liquid
保存溶液:0.01M PBS, pH 7.4.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献:
TNF-alpha inhibitor tanfanercept (HBM9036) improves signs and symptoms of dry eye in a phase 2 trial in the controlled adverse environment in China.PMID:35192105
Quintessence of currently approved and upcoming treatments for dry eye disease.PMID:39215848
TNF is a critical cytokine in age-related dry eye disease.PMID:37634571
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