佰乐博生物蛋白抗体推荐Anti-Influenza A virus (H5N1) HA/Hemagglutinin Antibody (SAA2067) (RVV03801)抗甲型流感病毒（H5N1）血凝素/血凝素抗体（SAA2067）蛋白抗体
一、中文名称：
Anti-Influenza A virus (H5N1) HA/Hemagglutinin Antibody (SAA2067) (RVV03801)，抗甲型流感病毒（H5N1）血凝素（HA）抗体（SAA2067），精品蛋白抗体试剂盒
二、产品描述
甲型流感病毒又称A型流行性感冒病毒（influenza A virus,IAV）属于正黏病毒科（Orthomyxoviridae），是单股负链分节段的RNA病毒。IAV基因组由8个节段构成，分别是聚合酶碱性蛋白2 (polymerase basic protein 2,PB2）、聚合酶碱性蛋白1 (polymerase basic protein 1,PB1）、聚合酶酸性蛋白(polymerase acid protein,PA)、血凝素(hemagglutinin,HA)、核蛋白（nucleoprotein,NP）、神经氨酸酶(neuraminidase,NA)、基质(matrix,M)蛋白和非结构蛋白（nonstructural protein,NS）节段。根据HA和NA的遗传性和抗原性的不同，可以将IAV分为18种HA亚型（H1-H18）和11种NA亚型（N1-N11）。
HA蛋白发挥其受体结合能力的前提是被宿主细胞蛋白酶（如跨膜丝氨酸蛋白酶TMPRSS2等）裂解为HA1和HA2两个亚基，而HA裂解位点氨基酸的不同，导致病毒的致病性也显著不同，同时HA蛋白的稳定性也能影响多种亚型流感病毒对家禽和哺乳动物的致病力。
三、产品详情
名称：Anti-Influenza A virus (H5N1) HA/Hemagglutinin Antibody (SAA2067)，抗甲型流感病毒（H5N1）血凝素（HA）抗体（SAA2067），体内中和抗体，活性抗体
货号：RVV03801
种属反应性：Influenza A virus (A/Viet Nam/1203/2004(H5N1)), Influenza A virus (strain A/Goose/Guangdong/1/1996 H5N1 genotype Gs/Gd)
宿主：Human
同种型：IgG1, kappa
克隆类型：Monoclonal
靶标：HA
浓度：1 mg/ml
内毒素水平：Please contact with the lab for this information.
纯度：>95% as determined by SDS - PAGE.
纯化方式：Protein A/G purified from cell culture supernatant.
Accession号：Q6DQ33, Q9Q0U6
克隆号：SAA2067
应用：ELISA, IF, SPR, WB
状态：Liquid
保存溶液：0.01M PBS, pH 7.4.
稳定性和存储：Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献：
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mSphere of Influence: Resolution of the Structure of an Influenza Virus Polymerase Is a Game Changer. PMID: 31434746
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Mutations to A/Puerto Rico/8/34 PB1 gene improves seasonal reassortant influenza A virus growth kinetics. PMID: 23116694
The Human Antimicrobial Protein Bactericidal/Permeability-Increasing Protein (BPI) Inhibits the Infectivity of Influenza A Virus. PMID: 27273104
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