一、中文名称：
Recombinant HPV16 E6/Protein E6 Protein, N-His，重组HPV16 E6/E6蛋白，N-His Strep，精品重组蛋白
二、产品描述
HPV16 E6蛋白在HPV相关癌症（如宫颈癌、头颈癌）的发病机制中具有核心作用，该蛋白的研究不仅深化了对HPV致癌机制的理解，还为开发靶向治疗策略（如基于核酶的基因治疗4或新型抗病毒肽6）提供了关键工具。其高特异性和功能性使其成为HPV相关基础研究与转化医学的核心试剂。
三、产品详情
名称：Recombinant HPV16 E6/Protein E6 Protein, N-His，重组HPV16 E6/E6蛋白，N-His Strep活性蛋白，重组蛋白
货号: YVV09001
表达系统: E. coli
种属: Human papillomavirus type 16
蛋白长度: Met1-Leu158
预测分子量: 21.34 kDa
性质: Recombinant
内毒素水平: Please contact with the lab for this information.
纯度: >90% as determined by SDS-PAGE.
Accession号: P03126
应用: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
状态: Lyophilized
保存溶液: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
重悬: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名: Protein E6, E6
四、参考文献：
Hyaluronan-CD44 interaction promotes HPV 16 E6 oncogene-mediated oropharyngeal cell carcinoma survival and chemoresistance. PMID: 30077625
Uneven distribution of HPV 16 E6 prototype and variant (L83V) oncoprotein in cervical neoplastic lesions. PMID: 10917543
Does the expression of HPV16/18 E6/E7 in head and neck squamous cell carcinomas relate to their clinicopathological characteristics? PMID: 19787251
HPV16 E6 natural variants exhibit different activities in functional assays relevant to the carcinogenic potential of E6. PMID: 16519914
Characterization of humoral immune responses against p16, p53, HPV16 E6 and HPV16 E7 in patients with HPV-associated cancers. PMID: 18785210
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
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