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InVivoMAb Anti-Human IL11 Antibody (X203) (VHD42201)蛋白抗体

发表时间:2025-02-24


一、中文名称:

InVivoMAb Anti-Human IL11 Antibody (X203) (VHD42201),InVivo单克隆抗人白细胞介素 11 抗体(X203),精品蛋白抗体试剂盒


二、产品描述

白介素11IL-11,Interleukin-11 or adipogenesis inhibitory factor)是一种促炎性细胞因子,属于IL-6细胞因子家族。细胞因子是细胞分泌的蛋白质或多肽,能够影响细胞间的相互作用和通讯。IL-11在正常情况下参与许多生理过程,包括造血、骨骼发育和免疫反应。然而,随着年龄的增长,IL-11在体内的水平会逐渐上升,尤其是在肝脏、脂肪组织和骨骼肌中。这种上升与许多与衰老相关的病理变化有关,例如代谢紊乱、慢性炎症和细胞衰老。

三、产品详情

名称:InVivoMAb Anti-Human IL11 Antibody (X203) (VHD42201),InVivo单克隆抗人白细胞介素 11 抗体(X203),体内中和抗体,活性抗体

货号:VHD42201

种属反应性:Human

宿主:Mouse

同种型:IgG2a, kappa

克隆类型:Monoclonal

靶标:Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, Oprelvekin, IL11

浓度:1 mg/ml

内毒素水平:Please contact with the lab for this information.

纯度:>95% as determined by SDS - PAGE.

纯化方式:Protein A/G purified from cell culture supernatant.

Accession号:P20809

克隆号:X203

应用:FuncS

状态:Liquid

保存溶液:0.01M PBS, pH 7.4.

稳定性和存储:Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.


四、参考文献:

A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.PMID:35140116

Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.PMID:31078624

Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.PMID:32592090

A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model.PMID:34667238

The Influence of IL-11 on Cardiac Fibrosis in Experimental Models: A Systematic Review.PMID:38392279

Automated chemical synthesis: from resins to instruments.PMID:9249755

Quantitative and qualitative assessment of enamel surface following five composite removal methods after bracket debonding.PMID:7781720


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