DVV02801 Palivizumab蛋白抗体
二、产品描述：Palivizumab (MEDI 493) 是一种人源化 RSV 特异性单克隆抗体，选择性抑制RSV A和B亚型F蛋白A抗原位点的表位，可用于预防呼吸道合胞病毒感染 (RSV)。
三、产品详情
货号 DVV02801
表达系统 Mammalian Cells
种属反应性 HRSV-A
宿主 Humanized
同种型 IgG1 kappa
克隆类型 Monoclonal
靶标 F Fusion glycoprotein F0 Fusion glycoprotein F2 p27 Intervening segment Pep27 Peptide 27 Fusion glycoprotein F1
浓度 2.47 mg/ml
内毒素水平 Please contact with the lab for this information
纯度 >95% as determined by SDS-PAGE
纯化方式 Protein A/G purified from cell culture supernatant
Accession 号 P03420
克隆号 Palivizumab
应用 Research Grade Biosimilar
状态 Liquid
保存溶液 0.01M PBS pH 7.4
稳定性和存储 Use a manual defrost freezer and avoid repeated freeze-thaw cycles Store at 4°C short term 1-2 weeks Store at -20°C 12 months Store at -80°C long term
别名 MEDI-493 CAS 188039-54-5
四、参考文献：
Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children: A Systematic Review and Network Meta-analysis. PMID: 36800182
Trends of respiratory syncytial virus sub-types in children hospitalised at a tertiary care centre in Jaipur during 2012-2014. PMID: 28303835
Immunoglobulin treatment for hospitalised infants and young children with respiratory syncytial virus infection. PMID: Update in:
Diagnosis and management of bronchiolitis. PMID: 17015575
Palivizumab for preventing severe respiratory syncytial virus (RSV) infection in children. PMID: 34783356
Respiratory syncytial virus infection in patients with hematological diseases: single-center study and review of the literature. PMID: 18181739
A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles. PMID: 23951084
Respiratory syncytial virus infection in 406 hospitalized premature infants: results from a prospective German multicentre database. PMID: 17943313
[Chinese experts consensus statement: diagnosis and treatment of cystic fibrosis (2023)]. PMID: 36990700
A phase 1a, first-in-human, randomized study of a respiratory syncytial virus F protein vaccine with and without a toll-like receptor-4 agonist and stable emulsion adjuvant. PMID: 27102821
Respiratory Syncytial Virus Hospitalizations in Healthy Preterm Infants: Systematic Review. PMID: 27093166
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