一、中文名称：
Recombinant HPV16 L2/Minor capsid protein L2 Protein, N-GST & C-His，重组HPV16 L2/主要衣壳蛋白L2蛋白，N-GST和C-His，精品重组蛋白
二、产品描述
HPV16 L2蛋白与主要衣壳蛋白L1协同组装病毒颗粒，在感染初期参与病毒与宿主细胞受体的结合及内吞过程，并介导病毒基因组向细胞核的转运，其保守表位可诱导广谱中和抗体，成为HPV治疗性疫苗（如嵌合VLPs疫苗）及广谱抗病毒药物开发的潜在靶点。该蛋白还可用于研究病毒入侵机制（如与细胞表面硫酸乙酰肝素蛋白聚糖的相互作用）或开发血清学检测方法（如ELISA检测L2特异性抗体）。
三、产品详情
名称：Recombinant HPV16 L2/Minor capsid protein L2 Protein, N-GST & C-His，重组HPV16 L2/主要衣壳蛋白L2蛋白，N-GST和C-His，活性蛋白，重组蛋白
货号: YVV20801
表达系统: E. coli
种属: Human papillomavirus type 16
蛋白长度: Arg2-Ala473
预测分子量: 79 kDa
性质: Recombinant
内毒素水平: Please contact with the lab for this information.
纯度: >90% as determined by SDS-PAGE.
Accession号: P03107
应用: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
状态: Lyophilized
保存溶液: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
重悬: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名: Minor capsid protein L2, L2
四、参考文献：
Involvement of Nucleophosmin (NPM1/B23) in Assembly of Infectious HPV16 Capsids. PMID: 26362430
Critical Residues Involved in the Coassembly of L1 and L2 Capsid Proteins of Human Papillomavirus 16. PMID: 34740725
A Peptide Derived from Sorting Nexin 1 Inhibits HPV16 Entry, Retrograde Trafficking, and L2 Membrane Spanning. PMID: 38909779
A peptide derived from sorting nexin 1 inhibits HPV16 entry, retrograde trafficking, and L2 membrane spanning. PMID: 34516991
Integrated genomic and molecular characterization of cervical cancer. PMID: Retraction in:
The l2 minor capsid protein of human papillomavirus type 16 interacts with a network of nuclear import receptors. PMID: 30946955
L2, the minor capsid protein of papillomavirus. PMID: 33802456
Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis. PMID: 27518844
Seroepidemiology of Human Papillomavirus 16 (HPV16) L2 and Generation of L2-Specific Human Chimeric Monoclonal Antibodies. PMID: 31600915
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
网址：https://www.biolabreagent.com/product/100/22064.html
武汉佰乐博生物技术有限公司作为法国Antibodysystem品牌亚洲区授权总代理。提供近3万种蛋白、抗体等核心生命科学试剂，旨在为生命科学科研工作者提供专业、全面、可靠的试剂产品。
试剂 | 耗材 | 定制 | 实验服务 | 供应链
免费热线：027-65279366 /18108604356
