一、中文名称：Research Grade Etanercept (DHB94429),研究级Etanercept类似物
二、产品描述
Etanercept 是一种结合肿瘤坏死因子 (TNF) 的二聚体融合蛋白，作为 TNF 抑制剂，Etanercept 竞争性地抑制 TNF-α 和 TNF-β 与细胞表面 TNF 受体的结合，使肿瘤坏死因子在生物学上失去活性。Etanercept 对风湿性关节炎、幼年特发性关节炎和斑块性银屑病有效。。
三、产品详情
名称：Research Grade Etanercept (DHB94429)
别名：CAS: 185243-69-0
货号：DHB94429
表达系统：Mammalian Cells
种属反应性：Human
宿主：Human
同种型：IgG1-Fc
克隆类型：Monoclonal
靶标：TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1
浓度：1 mg/ml
内毒素水平：Please contact with the lab for this information.
纯度：>95% as determined by SDS-PAGE.
纯化方式：Protein A/G purified from cell culture supernatant.
Accession号：P01375
克隆号：Etanercept
应用：Research Grade Biosimilar
状态：Liquid
保存溶液：0.01M PBS, pH 7.4.
稳定性和存储：Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献：
Etanercept biosimilar SB-4.PMID:30616405
GP2015: An Etanercept Biosimilar.PMID:28940172
Etanercept for the treatment of rheumatoid arthritis.PMID:29482402
Evaluation of Combination Therapy With Etanercept and Systemic Corticosteroids for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Multicenter Observational Study.PMID:35131514
Etanercept in the treatment of psoriatic arthritis.PMID:25455504
Etanercept in axial spondyloarthritis.PMID:35261349
Etanercept (SB4): A Review in Autoimmune Inflammatory Diseases.PMID:27455991
Etanercept for pemphigus vulgaris.PMID:30636400
[Etanercept].PMID:31204122
Etanercept as a successful therapy in autoinflammatory syndrome related to TRNT1 mutations: a case-based review.PMID:33646446
Etanercept for the treatment of non-radiographic axial spondyloarthritis.PMID:26788837
Etanercept-induced palisaded neutrophilic granulomatous dermatitis.PMID:33279312
Perispinal etanercept stroke trial design: PESTO and beyond.PMID:39177653
Etanercept Prevents Endothelial Dysfunction in Cafeteria Diet-Fed Rats.PMID:35206342
Safety update of etanercept treatment for moderate to severe plaque psoriasis.PMID:32178543
Etanercept-associated episcleritis: a pediatric case report of a paradoxical adverse reaction and review of the literature.PMID:37845415
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
网址：https://www.antibodysystem.com/product/659.html
武汉佰乐博生物技术有限公司作为法国Antibodysystem品牌亚洲区授权总代理。提供近3万种蛋白、抗体等核心生命科学试剂，旨在为生命科学科研工作者提供专业、全面、可靠的试剂产品。
试剂 | 耗材 | 定制 | 实验服务 | 供应链
免费热线：027-65279366 /18108604356
