一、中文名称:Anti-DNA G-quadruplex Structures Antibody (BG4),抗DNA G4链体抗体,抗DNA G-quadruplex结构抗体
二、产品描述
G-四链体(G-quadruplex)是由富含串联重复鸟嘌呤(G)的DNA或RNA折叠形成的高级结构。G-四分体(G-quartet)是四链体的结构单元,由Hoogsteen氢键连接4个G形成环状平面,两层或以上的四分体通过π-π堆积形成四链体。。
三、相关产品
Anti-DNA G-quadruplex Structures Antibody (BG4) (RGK60307)
Anti-DNA G-quadruplex Structures Antibody (BG4) (RGK60301)
四、产品详情
名称:Anti-DNA/RNA G-quadruplex Structures Antibody (BG4) (RGK60307)
货号:RGK60307
宿主:Mouse
同种型:IgG2a, kappa
克隆类型:Monoclonal
靶标:DNARNA G-quadruplex, DNA G-quadruplex structures, DNA G4, DNA G-quadruplex structures
浓度:0.91 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS-PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
克隆号:BG4
应用:ELISA, EMSA, ICC, IF, ChIP (ChIP-seq), WB
状态:Liquid
保存溶液:0.01M PBS, pH 7.4.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. (RGK60307)
五、参考文献:
G-quadruplex antibody attenuates human gastric cancer cell proliferation and promotes apoptosis through hTERT/telomerase pathway. PMID: 29771410
Characterization of G-quadruplex antibody reveals differential specificity for G4 DNA forms. PMID: 33084858
Side-by-side comparison of G-quadruplex (G4) capture efficiency of the antibody BG4 versus the small-molecule ligands TASQs. PMID: 37250775
Tolerance and decolorization potential of duckweed (Lemna gibba) to C.I. Basic Green 4. PMID: 34035402
Dual Binding of an Antibody and a Small Molecule Increases the Stability of TERRA G-Quadruplex. PMID: 26300569
Custom DNA Microarrays Reveal Diverse Binding Preferences of Proteins and Small Molecules to Thousands of G-Quadruplexes. PMID: 32216326
Human ribosomal G-quadruplexes regulate heme bioavailability. PMID: 32817343
Development of a novel light-up probe for detection of G-quadruplexes in stress granules. PMID: 35902691
A novel flower-specific Arabidopsis gene related to both pathogen-induced and developmentally regulated plant beta-1,3-glucanase genes. PMID: 10092183
Application of microalga Chlamydomonas sp. for biosorptive removal of a textile dye from contaminated water: modelling by a neural network. PMID: 20184007
RNA G-quadruplex structures control ribosomal protein production. PMID: 34815422
Dual binding of an antibody and a small molecule increases the stability of TERRA G-quadruplex. PMID: 25421962
Effect of the interaction between dye and acetic acid on the decomposition of Basic Green 4 with additive by ozone. PMID: 24117080
Phase Separation Modulates the Formation and Stabilities of DNA Guanine Quadruplex. PMID: 37388701
G4 Sensing Pyridyl-Thiazole Polyamide Represses c-KIT Expression in Leukemia Cells. PMID: 33851760
Waste of Mytella Falcata shells for removal of a triarylmethane biocide from water: Kinetic, equilibrium, regeneration and thermodynamic studies. PMID: 32629072
BG-flow, a new flow cytometry tool for G-quadruplex quantification in fixed cells. PMID: 33706790
Single-Molecule Analysis of the Improved Variants of the G-Quadruplex Recognition Protein G4P. PMID: 37373425
An organic molecular compound for in situ identification of mitochondrial G-quadruplexes in live cells. PMID: 34940779
G-quadruplexes Mark Sites of Methylation Instability Associated with Ageing and Cancer. PMID: 36140833
Epigenomic features of DNA G-quadruplexes and their roles in regulating rice gene transcription. PMID: 34893906
DNA G-Quadruplex Recognition In Vitro and in Live Cells by a Structure-Specific Nanobody. PMID: 36488193
Synthesis, conformation and cytotoxic activity of short hybrid peptides containing conformationally constrained 1-(aminomethyl)cyclohexanecarboxylic acid and gabapentin. PMID: 36279986
Epigenomic Features and Potential Functions of K+ and Na+ Favorable DNA G-Quadruplexes in Rice. PMID: 35955535
Cellular Antisense Activity of PNA-Oligo(bicycloguanidinium) Conjugates Forming Self-Assembled Nanoaggregates. PMID: 26010253
Telomere and G-Quadruplex Colocalization Analysis by Immunofluorescence Fluorescence In Situ Hybridization (IF-FISH). PMID: 31127589
Physicochemical Characteristics of Black Garlic after Different Thermal Processing Steps. PMID: 28078257
Subcellular Duplex DNA and G-Quadruplex Interaction Profiling of a Hexagonal PtII Metallacycle. PMID: 31002438
Small Molecule Driven Stabilization of Promoter G-Quadruplexes and Transcriptional Regulation of c-MYC. PMID: 29956928
BG-4 from Bitter Gourd (Momordica charantia) Differentially Affects Inflammation In Vitro and In Vivo. PMID: 31197086
Cockayne Syndrome B Protein Selectively Resolves and Interact with Intermolecular DNA G-Quadruplex Structures. PMID: 34855372
Bio-prospecting of soil Streptomyces and its bioassay-guided isolation of microbial derived auxin with antifungal properties. PMID: 29884344
Elevated levels of G-quadruplex formation in human stomach and liver cancer tissues. PMID: 25033211
Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer. PMID: 35166828
Activation-induced cytidine deaminase localizes to G-quadruplex motifs at mutation hotspots in lymphoma. PMID: 33094287
A Cytoplasm-Specific Fluorescent Ligand for Selective Imaging of RNA G-Quadruplexes in Live Cancer Cells. PMID: 36971407
Characterization of G4 DNA formation in mitochondrial DNA and their potential role in mitochondrial genome instability. PMID: 34228888
Single-molecule analysis of the improved variants of the G-quadruplex recognition protein G4P. PMID: 37214990
Light-induced in situ chemical activation of a fluorescent probe for monitoring intracellular G-quadruplex structures. PMID: 34477654
BrdU immuno-tagged G-quadruplex ligands: a new ligand-guided immunofluorescence approach for tracking G-quadruplexes in cells. PMID: 34875077
Synthesis of carboxymethylated β-glucan from naked barley bran and its antibacterial activity and mechanism against Staphylococcus aureus. PMID: 32564831
Aflatoxicosis chemoprevention by probiotic Lactobacillius and lack of effect on the major histocompatibility complex. PMID: 24997556
A naphthyridine-indole ligand for selective stabilization of G-quadruplexes and conformational conversion of hybrid topology. PMID: 34560615
Flucytosine analogues obtained through Biginelli reaction as efficient combinative antifungal agents. PMID: 28189732
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