一、中文名称:Anti PEG Antibody,PEG抗体
二、产品描述
PEG是聚乙二醇的常用缩写,是由重复的乙二醇单元组成的复合物。具有高亲水性、无毒、无抗原性且生物兼容性等特点。PEG化修饰会改变药物的物理化学性质,提高血浆半衰期,延长吸收时间,还能影响药物与细胞受体的结合亲和力,改善肿瘤靶向性。在PEG化修饰药物的研究中,PEG抗体是非常重要的研究工具。抗PEG抗体可用于监测药物的药代动力学,包括分布、代谢和排泄以及聚乙二醇化蛋白质或分子(例如纳米颗粒)的质量控制。Antibodysystem PEG系列抗体适用于ELISA、WB和HC。
三、相关产品
Anti-PEG Antibody (E11.2#) (RGK24701)
Anti-PEG Antibody (6A9/PEG.2) (RGK24702)
Anti-PEG Antibody (14B5/PEG.1a) (RGK24703)
Anti-PEG Antibody (14B5/PEG.1b) (RGK24704)
Anti-PEG Antibody (3.3.1) (RGK24705)
Anti-PEG Antibody (2B5) (RGK24706)
Anti-PEG Antibody (32D6)(RGK24707)
Anti-PEG Antibody (AGP3) (RGK24708)
Anti-PEG Antibody (6.3) (RGK24709)
Anti-PEG Antibody (15-2b)(RGK24710)
四、产品详情
名称:Anti-PEG Antibody (E11.2#) (RGK24701)
别名:PEG, Poly(ethylene glycol), Polyethylene glycol
货号:RGK24701
宿主:Mouse
同种型:IgG1, kappa
克隆类型:Monoclonal
靶标:PEG, Poly(ethylene glycol), Polyethylene glycol
浓度:1 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS-PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
克隆号:E11.2#
应用:ELISA, WB
状态:Liquid
保存溶液:0.01M PBS, pH 7.4.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献:
Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation.PMID:27369864
["PEG dilemma" for liposomes and its solving approaches].PMID:26118102
Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes.PMID:31336703
Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route.PMID:37355210
Exosome isolation based on polyethylene glycol (PEG): a review.PMID:39702782
Quantitation of PEG on PEGylated Gold Nanoparticles Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection: Version 1.0.PMID:39012983
PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication.PMID:25547369
Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use.PMID:26191379
Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine.PMID:38469811
Stepwise PEG synthesis featuring deprotection and coupling in one pot.PMID:35079293
The Importance of Poly(ethylene glycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation.PMID:32024289
Missing PEG tube found at the ileocecal valve.PMID:34401032
Polyethylene Glycol.PMID:30694626
Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice.PMID:36632951
The uses and properties of PEG-linked proteins.PMID:1458545
Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture.PMID:36641121
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