一、中文名称:Anti-Human HLA-A/B/C Antibody (HB95)(MHM00101), 抗人HLA-A,B,C抗体
二、产品描述
HLA-I类主要组织相容性复合体(MHC)抗原是核细胞表面表达的内在膜糖蛋白,并与不变的β2微球蛋白非共价结合。它们携带重要的外来决定簇,这些决定簇对于细胞毒性T细胞的免疫识别至关重要,因此在抗病毒和抗肿瘤防御中发挥关键作用。人类HLA-I类抗原由HLA-A、HLA-B和HLA-C分子代表。HLA和MHC抗体在免疫肽组学中扮演重要角色,通过高效液相色谱与串联质谱联用技术,促进新抗原的鉴定和表征。
三、产品详情
名称:Anti-Human HLA-A/B/C Antibody (HB95)(MHM00101)
货号:MHM00101
种属反应性:Human
宿主:Mouse
同种型:IgG2a
克隆类型:Monoclonal
靶标:HLAA, Human leukocyte antigen A, HLA class I histocompatibility antigen, A alpha chain, HLA-A, HLA-B, HLA class I histocompatibility antigen, B alpha chain, Human leukocyte antigen B, HLAB, HLA-Cw, HLA-C, Human leukocyte antigen C, HLAC, HLA class I histocompatibility antigen, C alpha chain
浓度:1 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS-PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
Accession号:P04439, P01889, P10321
克隆号:HB95
应用:ELISA, FCM
状态:Liquid
保存溶液:0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献:
HLA-A*02:1093, a variant of HLA-A*02:01:01:01 detected in two Spanish individuals.PMID:37681690
HLA-A*02:411 identified in a platelet donor from China.PMID:32725697
The novel HLA-A allele, HLA-A*01:353.PMID:33034166
HLA-A*11:263 is found on the haplotype: HLA-A*11:263-C*03:04:01-B*13:01.PMID:33040442
The novel HLA-A*24:520 allele was identified in a Chinese individual.PMID:35842716
The novel HLA-A*26:174 allele was identified in a Chinese individual.PMID:34029012
Identification of the novel HLA-A*11:423 allele by sequencing-based typing.PMID:36567406
Characterization of the novel HLA-A*24:587 allele by sequencing-based typing.PMID:37067775
Characterization of the novel HLA-A*24:585 allele by sequencing-based typing.PMID:36754583
Identification of four novel HLA-A alleles.PMID:32277603
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