武汉佰乐博生物技术有限公司
   
     
联系热线
  • 联系人:方经理
  • 电 话:027-65279366
  • 邮箱:products@biolabreagent.com
  • 地 址:武汉市东湖新技术开发区神墩四路666号C栋

Research Grade Briobacept

发表时间:2025-02-26


一、中文名称:

Research Grade Briobacept,科研级Briobacept


二、产品描述

Briobacept (BR 3FC) 是一种重组糖蛋白,由 2 个来自 BLyS 受体 (BR3) 和人 IgG1 Fc 结构域组成。Briobacept 选择性靶向 BLyS BAFF),能够诱导 B 细胞凋亡 (apoptosis)。Briobacept 可用于类风湿关节炎 (RA) 的研究。

三、产品详情

名称:Research Grade Briobacept,科研级Briobacept

货号:DHJ85303

表达系统:Mammalian Cells

种属反应性:Human

同种型:Fusion - [TNFRSF13C (tumor necrosis factor receptor (TNFR) superfamily member 13C, BAFFR, BR3, B cell activating factor receptor, CD268)] 2 - IGHG1 Fc (Fragment constant)

靶标:BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor

浓度:1 mg/ml

内毒素水平:Please contact with the lab for this information.

纯度:>95% as determined by SDS-PAGE.

纯化方式:Protein A/G purified from cell culture supernatant.

Accession 号:Q9Y275

克隆号:Briobacept

应用:Research Grade Biosimilar

状态:Liquid

保存溶液:0.01M PBS, pH 7.4.

稳定性和存储:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.

别名:BR3-Fc,SS-79, CAS: 869881-54-9


四、参考文献:

The efficacy of novel B cell biologics as the future of SLE treatment: a review.PMID:25149393

The immunological basis of B-cell therapy in systemic lupus erythematosus.PMID:20374380

[Novel B-cell directed strategies for the treatment of rheumatic diseases].PMID:19513729

Gateways to clinical trials. December 2008.PMID:19271026

Emerging therapeutics for rheumatoid arthritis.PMID:18937634


详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司

网址:https://www.biolabreagent.com/product/99/5727.html

武汉佰乐博生物技术有限公司作为法国Antibodysystem品牌亚洲区授权总代理。提供近3万种蛋白、抗体等核心生命科学试剂,旨在为生命科学科研工作者提供专业、全面、可靠的试剂产品。

试剂 | 耗材 | 定制 | 实验服务 | 供应链

免费热线:027-65279366 /18108604356


联系方式
手机:18108604356
微信扫一扫