一、中文名称：
Research Grade Anti-Human IL11 Antibody (X203) (DHD42201)，抗 Human IL11 抗体 (X203) 单克隆抗体，精品蛋白抗体试剂盒
二、产品描述
白介素11（IL-11,Interleukin-11 or adipogenesis inhibitory factor）是一种促炎性细胞因子，属于IL-6细胞因子家族。细胞因子是细胞分泌的蛋白质或多肽，能够影响细胞间的相互作用和通讯。IL-11在正常情况下参与许多生理过程，包括造血、骨骼发育和免疫反应。然而，随着年龄的增长，IL-11在体内的水平会逐渐上升，尤其是在肝脏、脂肪组织和骨骼肌中。这种上升与许多与衰老相关的病理变化有关，例如代谢紊乱、慢性炎症和细胞衰老。
三、产品详情
名称：Research Grade Anti-Human IL11 Antibody (X203) (DHD42201)，抗 Human IL11 抗体 (X203) 单克隆抗体，体内中和抗体，活性抗体
货号：DHD42201
表达系统：Mammalian Cells
种属反应性：Human
宿主：Human
同种型：IgG1, kappa
克隆类型：Monoclonal
靶标：Adipogenesis inhibitory factor, AGIF, IL11, IL-11, Interleukin-11, Oprelvekin
浓度：2.7 mg/ml
内毒素水平：Please contact with the lab for this information.
纯度：>95% as determined by SDS - PAGE.
纯化方式：Protein A/G purified from cell culture supernatant.
Accession号：P20809
克隆号：EnX203
应用：Research Grade Biosimilar
状态：Liquid
保存溶液：0.01M PBS, pH 7.4.
稳定性和存储：Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.
别名：EnX203, EnX 203, EnX - 203, X203
四、参考文献：
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.PMID:35140116
Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.PMID:31078624
Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.PMID:32592090
A neutralizing IL-11 antibody reduces vessel hyperplasia in a mouse carotid artery wire injury model.PMID:34667238
The Influence of IL-11 on Cardiac Fibrosis in Experimental Models: A Systematic Review.PMID:38392279
Automated chemical synthesis: from resins to instruments.PMID:9249755
Quantitative and qualitative assessment of enamel surface following five composite removal methods after bracket debonding.PMID:7781720
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
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