一、中文名称:
Research Grade Anti-Human CDH3/P-cadherin (PCA062) (DHD50503),Anti CDH3/P-cadherin Antibody 克隆号PCA062,精品蛋白抗体试剂盒
二、产品描述
Anti CDH3/P-cadherin Antibody 克隆号PCA062,钙粘蛋白-3(CDH3)是一种单通道I型膜蛋白,属于钙粘蛋白超家族。CDH3是一种钙依赖性细胞间粘附糖蛋白,由五个细胞外钙粘蛋白重复序列、一个跨膜区域和一个高度保守的细胞质尾部组成。CDH3在一些正常上皮组织和一些癌细胞系中表达。CDH3在连接细胞中优先以同亲性方式与自身相互作用。CDH3参与乳腺癌和前列腺癌杂合性事件的丧失。CDH3突变与幼年性黄斑营养不良的先天性少毛症有关。
三、产品详情
名称:Research Grade Anti-Human CDH3/P-cadherin (PCA062) (DHD50503),Anti CDH3/P-cadherin Antibody 克隆号PCA062,体内中和抗体,活性抗体
货号:DHD50503
表达系统:Mammalian Cells
种属反应性:Human
宿主:Human
同种型:IgG1
克隆类型:Monoclonal
靶标:Placental cadherin, CDH3, Cadherin-3, P-cadherin, CDHP
浓度:2.04 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS - PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
Accession号:P22223
克隆号:PCA062
应用:Research Grade Biosimilar
状态:Liquid
保存溶液:0.01M PBS, pH 7.4.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.
别名:PCA062
四、参考文献:
CDH3/P-Cadherin regulates migration of HuCCT1 cholangiocarcinoma cells. PMID: 21189991
CDH3 gene related hypotrichosis and juvenile macular dystrophy - A case with a novel mutation. PMID: 29260097
New CDH3 mutation in the first Spanish case of hypotrichosis with juvenile macular dystrophy, a case report. PMID: 28061825
Novel CDH3 variants in Brazilian families with hypotrichosis and juvenile macular dystrophy revealed by exome sequencing. PMID: 31696509
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
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