一、中文名称：
Recombinant Tirzepatide Protein, N-His-KSI，替尔泊肽重组蛋白
二、产品描述
Tirzepatide(LY-3298176)是葡萄糖依赖性多肽(GIP)和胰高血糖素样肽-1 (GLP-1)受体双重激动剂，具有神经保护活性，可改善血压并降低低密度脂蛋白（LDL）胆固醇和甘油三酯，可以用于研究糖尿病和肥胖症。与杜拉鲁肽相比,Tirzepatide (LY-3298176)在血糖控制和体重减轻方面的疗效明显更好。
三、产品详情
名称：Recombinant Tirzepatide Protein, N-His-KSI，替尔泊肽重组蛋白
货号：YHK13902
表达系统：E. coli
种属：Homo sapiens (Human)
蛋白长度：2*Tirzepatide [Tyr - Aib - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Tyr - Ser - Ile - Aib - Leu - Asp - Lys - Ile - Ala - Gln - Lys - Ala - Phe - Val - Gln - Trp - Leu - Ile - Ala - Gly - Gly - Pro - Ser - Ser - Gly - Ala - Pro - Pro - Pro - Ser - NH2]2
预测分子量：24.17 kDa
性质：Recombinant
内毒素水平：Please contact with the lab for this information.
纯度：>90% as determined by SDS - PAGE.
Accession号：CAS: 2023788 - 19 - 2
应用：ELISA, Immunogen, SDS - PAGE, WB, Bioactivity testing in progress
状态：Lyophilized
保存溶液：Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
重悬：Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输：In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储：Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名：Tirzepatide, LY3298176, GIP/GLP - 1 RA, TZP,替尔泊肽
四、参考文献：
Tirzepatide: First Approval. PMID: 35830001
Tirzepatide: A Systematic Update. PMID: 36498958
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist. PMID: 32730231
Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes. PMID: 34170647
Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial. PMID: 37385275
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