介绍:Digoxin是 Na+/K+-ATPase 的有效抑制剂。该抗体对地高辛(一种从毛地黄植物中提取的心脏糖苷)具有特异性。地高辛用于治疗心房颤动、心房扑动和心力衰竭等心脏疾病,其作用是抑制Na+/K+ atp酶。然而,该药的治疗指标非常狭窄,并可能引起毒副作用。由26-10制备的Fab片段,可以中和地高辛的活性,在洋地黄过量的情况下可以用作解毒剂。抗地高辛单克隆抗体也可以用来测量药物的血清水平,作为治疗的指导,并且在抗体和抗原相互作用动力学的研究中是有用的。
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链接:https://www.antibodysystem.com/product/8567.html
名称:Anti Digoxin Antibody (26G10)地高辛单克隆抗体
中文名:地高辛;异羟洋地黄毒苷
别名:Digoxin, DGX, CAS: 20830-75-5,digoxinum,12β-hydroxydigitoxin,ChEBI: 4551, 26-10#, 26G10,Digoxin Monoclonal Antibody
货号:RGK23001
宿主:Mouse
应用:CLIA, Dot, ELISA, IP, RIA, WB
形式:Liquid
纯度:>95%
克隆:Monoclonal
同型:IgG2a, kappa
内毒素水平:Please contact with the lab for this information.
用途范围:仅用于科研
储存:Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
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参考文献:
Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritis. PMID: 34853001
Role of Digoxin in Atrial Fibrillation. PMID: 27067743
Digoxin protects against intervertebral disc degeneration via TNF/NF-kappaB and LRP4 signaling. PMID: 37790932
Digoxin--issues and controversies. PMID: 3510096
Digoxin. PMID: 1120872
Digoxin--a redundant drug in congestive cardiac failure. PMID: 2488085
Digoxin toxicity in the aged. Characterising and avoiding the problem. PMID: 1794026
Digoxin Exhibits Neuroprotective Properties in a Rat Model of Dementia. PMID: 35064518
[Digoxin]. PMID: 3185769
[A baby with digoxin toxicity]. PMID: 25944069
A nomogram for digoxin therapy. PMID: 4600984
Clinical pharmacokinetics of digoxin 1980. PMID: 6988136
Digoxin therapy: textbooks, theory and practice. PMID: 22216507
Digoxin bioavailability. PMID: 82124
A perspective on re-evaluating digoxin's role in the current management of patients with chronic systolic heart failure: targeting serum concentration to reduce hospitalization and improve safety profile. PMID: 24574198
Digoxin in the 1980s. PMID: 3309595
Computer-assisted digoxin therapy. PMID: 4763409
Quinidine-digoxin interaction. PMID: 7436201
Clinical pharmacology of digoxin. PMID: 4558886
How to digitalize and to maintain optimal digoxin levels in congestive heart failure. PMID: 2488083
Digoxin: placental transfer, effects on the fetus, and therapeutic use in the newborn. PMID: 1102216
Digoxin in heart failure. PMID: 2569093
Serum digoxin concentrations in atrial fibrillation: a review. PMID: 7049644
Digoxin therapeutics: straightening out the facts. PMID: 1513197
The rational pharmacology of digoxin. PMID: 1389200
Population Pharmacokinetic Studies of Digoxin in Adult Patients: A Systematic Review. PMID: 33616855
Digoxin Use and Subsequent Outcomes Among Patients in a Contemporary Atrial Fibrillation Cohort. PMID: 26112191
Understanding digoxin use in the elderly patient. PMID: 2253445
Pharmacokinetics of digoxin in the rat. PMID: 3407
Is there an expanded role for digoxin in patients with heart failure and sinus rhythm? A protagonist viewpoint. PMID: 9220052
Digoxin metabolism in patients. PMID: 666466
Serum digoxin test in perspective. PMID: 912635
Bioavailability of digoxin. PMID: 4113330