货号	YHC93301
产品名称	Recombinant Human CKB Protein, N-His
规格	100 μg
价格	1880
状态	Lyophilized
储存缓冲液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
纯度	>90% as determined by SDS-PAGE.
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
内毒水平	Please contact with the lab for this information.
表达系统	E. coli
Accession	P12277
蛋白长度	Pro2-Lys381
预测分子量	44.82 kDa
稳定性与储存条件	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
别名	Creatine phosphokinase B-type, Creatine kinase B-type, CKBB, CPK-B, Brain creatine kinase, Creatine kinase B chain, B-CK, CKB
物种	Homo sapiens (Human)
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
备注	For research use only.

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本产品经SDS-PAGE验证，纯度 > 90%，满足大多数免疫检测及细胞生物学实验要求。

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背景介绍：

CKB（脑型肌酸激酶）属于肌酸激酶亚型，广泛表达于神经组织、平滑肌等多种细胞。该蛋白参与细胞能量代谢，催化高能磷酸基团转运，维持胞内能量稳态，常作为细胞能量代谢相关研究的分子标识。

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前沿相关研究：

1.Fully automated closed-loop insulin delivery in adults with type 2 diabetes: an open-label, single-center, randomized crossover trial., PMID:36631592

2.Ubiquitin protein E3 ligase ASB9 suppresses proliferation and promotes apoptosis in human spermatogonial stem cell line by inducing HIF1AN degradation., PMID:36683111

3.Implanted Tissue-Engineered Vascular Graft Cell Isolation with Single-Cell RNA Sequencing Analysis., PMID:36719780

4.Proteomic and bioinformatic analysis of human endometrium from polycystic ovarian syndrome with and without insulin resistance., PMID:36750132

5.Investigation of the dual role of acyl phloroglucinols as a new hope for antibacterial and anti-SARS-CoV-2 agents employing integrated in vitro and multi-phase in silico approaches., PMID:36927239

6.Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa., PMID:37101650

7.Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function., PMID:37156912

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AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
【核心产品线】核心产品囊括：病毒/细菌相关抗体&蛋白、In Vivo功能性抗体、低背景流式抗体、高特异性纳米抗体、活性蛋白、PK/ADA试剂盒、特色小分子抗体、DNA/RNA抗体、传统多抗、经典内参及标签抗体。
【应用领域】目前，旗下产品已全面覆盖热门病毒与超级细菌、寄生虫、tumor相关研究、认知衰退类神经退行性疾病（阿尔茨海默症）、神经组织衰老与神经元功能紊乱相关模型、变态反应与超敏应答、免疫负调控与免疫激活等多个关键科研领域。
【产品优势】高纯度、高特异性、高灵敏度重组蛋白、抗体以及ELISA 试剂盒。覆盖HRP、Biotin、FITC、PE、APC、PerCP等多种标记类型；适用于Human、Mouse、Rat、Rabbit、Goat等多个种属。 经WB、ELISA、IHC、IF、IP、FCM等多种实验验证，具有优异的特异性、灵敏度和批间一致性。产品常备现货，支持快速交付，并提供详实验证数据及高分文献支持，为tumor相关研究、免疫学、细胞生物学及药物研发提供可靠研究工具。
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以上产品仅用于科研,产品信息以产品说明书为准