货号	YHC38201
产品名称	Recombinant Human FGF2/bFGF Protein, C-His
规格	100 μg
价格	1880
状态	Lyophilized
储存缓冲液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
纯度	>90% as determined by SDS-PAGE.
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
内毒水平	Please contact with the lab for this information.
表达系统	E. coli
Accession	P09038
蛋白长度	Pro143-Ser288
预测分子量	17.61 kDa
稳定性与储存条件	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
别名	bFGF, FGF2, Basic fibroblast growth factor, HBGF-2, FGFB, FGF-2, Heparin-binding growth factor 2, Fibroblast growth factor 2
物种	Homo sapiens (Human)
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
备注	For research use only.

---

背景介绍：

FGF2（碱性成纤维细胞生长因子）属于生长因子蛋白，调控细胞增殖迁移、胞外基质重塑与组织修护，多种细胞均可分泌。表达异常会扰乱组织生长稳态，是细胞增殖、组织修复方向常用研究靶点。

---

前沿相关研究：

1.TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts.PMID: 40383937.

2.Targeting cancer-associated fibroblast autophagy renders pancreatic cancer eradicable with immunochemotherapy by inhibiting adaptive immune resistance.PMID:38174993.

3.Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells.PMID: 21750150.

4.Molecular and clinical significance of fibroblast growth factor 2 (FGF2/bFGF) in malignancies of solid and hematological cancers for personalized therapies.PMID: 27007053.

5.Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotype.PMID: 9247302.

6.Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity. PMID: 25483966.

7.Fibroblast growth factor-2 regulates myocardial infarct repair: effects on cell proliferation, scar contraction, and ventricular function. PMID:17872976.

8.Inhibition of vascular smooth muscle cell proliferation by a novel fibroblast growth factor receptor antagonist.PMID: 11744033.

---

AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
【核心产品线】 核心产品囊括：病毒/细菌相关抗体&蛋白、In Vivo功能性抗体、低背景流式抗体、高特异性纳米抗体、活性蛋白、PK/ADA试剂盒、特色小分子抗体、DNA/RNA抗体、传统多抗、经典内参及标签抗体。
【应用领域】 目前，旗下产品已全面覆盖热门病毒与超级细菌、寄生虫、tumor相关研究、认知衰退类神经退行性疾病（阿尔茨海默症）、神经组织衰老与神经元功能紊乱相关模型、变态反应与超敏应答、免疫负调控与免疫激活等多个关键科研领域。
【产品优势】 高纯度、高特异性、高灵敏度重组蛋白、抗体以及ELISA 试剂盒。覆盖HRP、Biotin、FITC、PE、APC、PerCP等多种标记类型；适用于Human、Mouse、Rat、Rabbit、Goat等多个种属。 经WB、ELISA、IHC、IF、IP、FCM等多种实验验证，具有优异的特异性、灵敏度和批间一致性。产品常备现货，支持快速交付，并提供详实验证数据及高分文献支持，为tumor相关研究、免疫学、细胞生物学及药物研发提供可靠研究工具。
如果您对我们的产品感兴趣,请联系027-65279366
以上产品仅用于科研,产品信息以产品说明书为准