货号	YHC37501
产品名称	Recombinant Human NMB Protein, N-GST
规格	100 μg
价格	1880
状态	Lyophilized
储存缓冲液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
纯度	>90% as determined by SDS-PAGE.
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
内毒水平	Please contact with the lab for this information.
表达系统	E. coli
Accession	P08949
蛋白长度	Ala25-Lys121
预测分子量	37.66 kDa
稳定性与储存条件	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重悬	Reconstitute in sterile water for a stock solution.
别名	NMB, Neuromedin-B
物种	Homo sapiens (Human)
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
备注	For research use only.

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背景介绍：

NMB（神经介素 B）是一类神经肽分子，广泛分布于中枢及外周组织。通过结合对应的受体参与信号传导，调控摄食行为、痛觉感知与体液调节活动。其表达水平异常会扰乱机体生理平衡，是神经调节方向研究的常用靶点。

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前沿相关研究：

1.Phase 1 study of the pharmacokinetics and clinical proof-of-concept activity of a biofilm-disrupting human monoclonal antibody in patients with chronic prosthetic joint infection of the knee or hip., PMID:39012102

2.Evaluation of a bimodal, matched pair theranostic agent targeting prostate-specific membrane antigen., PMID:39032262

3.The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects., PMID:39033550

4.Prostaglandin E2 regulates the plasminogen activator pathway in human endometrial endothelial cells: a new in vitro model to investigate heavy menstrual bleeding., PMID:39038609

5.Seasonal Proteome Variations in Orbicella faveolata Reveal Molecular Thermal Stress Adaptations., PMID:39051238

6.Functional status and quality of life in older patients with advanced esophageal squamous cell cancer receiving second-line nivolumab ± ipilimumab therapy: A post hoc analysis of the phase 2, multicenter RAMONA study., PMID:39097500

7.Synthesis and preclinical evaluation of [18F]AlF-NODA-MP-C6-CTHRSSVVC as a PET tracer for CD163-positive tumor-infiltrating macrophages., PMID:39151305

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AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
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