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| 产地 | France |
| 品牌 | AntibodySystem |
| 货号 | YHC32601 |
| 用途 | 仅用于科研 |
| 包装规格 | 100 μg |
| 纯度 | 0.95% |
| CAS编号 | |
| 是否进口 | 否 |
| 货号 | YHC32601 |
| 产品名称 | Recombinant Human SOD3 Protein, N-His |
| 规格 | 100 μg |
| 价格 | 1880 |
| 状态 | Lyophilized |
| 储存缓冲液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒水平 | Please contact with the lab for this information. |
| 表达系统 | E. coli |
| Accession | P08294 |
| 蛋白长度 | Trp19-Ala240 |
| 预测分子量 | 26.45 kDa |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 别名 | Extracellular superoxide dismutase [Cu-Zn], SOD3, EC-SOD |
| 物种 | Homo sapiens (Human) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
背景介绍:
SOD3(细胞外超氧化物歧化酶3)是一种含铜锌的分泌型抗氧化酶,主要分布于细胞外基质。其核心功能是催化超氧阴离子分解,清除胞外活性氧,从而维持机体氧化还原稳态。该蛋白在维持组织氧化还原平衡、保护内皮屏障完整性及响应机体代谢波动中发挥重要作用,广泛参与氧化性损伤修复、组织微环境重构及循环系统稳态调节等病理生理过程,是氧化应激相关疾病机制研究的重要靶点。
1.Transgenerational response of glucose metabolism in Caenorhabditis elegans exposed to 6-PPD quinone., PMID:39486626
2.Elucidating the roles of SOD3 correlated genes and reactive oxygen species in rare human diseases using a bioinformatic-ontology approach., PMID:39480826
3.Specific analysis of SOD1 enzymatic activity in CSF from ALS patients with and without SOD1 mutations., PMID:39490682
4.Polysaccharides from Ziziphus jujuba prolong lifespan and attenuate oxidative stress in Caenorhabditis elegans via DAF-16 and SKN-1., PMID:39528176
5.Dysregulated Activation of Hippo-YAP1 Signaling Induces Oxidative Stress and Aberrant Development of Intrahepatic Biliary Cells in Biliary Atresia., PMID:39579985
6.Species-specific responses to di (2-ethylhexyl) phthalate reveal activation of defense signaling pathways in California sea lion but not in human skeletal muscle cells in primary culture., PMID:39647646
7.Lifespan Extension and Motor Function Improvement Effects of Whale Meat Extract in Caenorhabditis elegans., PMID:39684544
Q1:这款重组人SOD3蛋白的纯度是多少?
A:本产品经SDS-PAGE检测,纯度大于90%,可满足各类常规科研实验需求。
Q2:该SOD3蛋白如何复溶配制储备液?
A:可直接使用无菌水复溶配制储备液,详细标准化复溶操作步骤可查阅产品配套说明书。
Q3:这款重组SOD3蛋白的储存条件与保质期是什么?
A:日常频繁使用可保存于2~8℃;长期保存需置于-20~-80℃环境,自收货之日起保质期12个月。储存需使用手动除霜冰箱,避免反复冻融,防止蛋白活性流失。
Q4:该重组人SOD3蛋白可应用于哪些实验?
A:产品适用于ELISA、免疫原制备、SDS-PAGE、WB等实验,目前生物活性检测正在推进中,仅可用于科研用途。