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| 产地 | France |
| 品牌 | AntibodySystem |
| 货号 | EHC16001 |
| 用途 | 仅用于科研 |
| 包装规格 | 100 μg |
| 纯度 | 0.95% |
| CAS编号 | |
| 是否进口 | 否 |
| 货号 | EHC16001 |
| 产品名称 | Recombinant Human CD54/ICAM1 Protein, C-His |
| 规格 | 100 μg |
| 价格 | 2880 |
| 状态 | Lyophilized |
| 储存缓冲液 | Lyophilized from a solution in PBS pH7.4,1mM EDTA, 4%trehalose,1% mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒水平 | Please contact with the lab for this information. |
| 表达系统 | Mammalian Cells |
| Accession | P05362 |
| 蛋白长度 | Met1-Glu480 |
| 预测分子量 | 53 kDa |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution. |
| 别名 | ICAM1, Major group rhinovirus receptor, CD54, ICAM-1, Intercellular adhesion molecule 1 |
| 物种 | Homo sapiens (Human) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
CD54/ICAM1(细胞间黏附分子1)属于免疫球蛋白超家族膜蛋白,介导细胞之间相互黏附,参与免疫细胞迁移、细胞识别等生理过程。该蛋白可被外界刺激诱导上调表达,表达紊乱会破坏组织微环境稳定,是细胞黏附及免疫生理研究的常用靶点。
前沿相关研究:
1.Relation of ICAM-1 and VCAM-1 markers in COVID-19 patients in Kirkuk province., PMID:39240630
2.A one-way street recognition approach to mediate allogeneic immune cell therapies., PMID:39241752
3.LPI-GPR55 promotes endothelial cell activation and inhibits autophagy through inducing LINC01235 expression., PMID:39316662
4.Intercellular adhesion molecule-1 (ICAM-1): From molecular functions to clinical applications in cancer investigation., PMID:39317271
5.Human rhinovirus 16 induces an ICAM-1-PKR-ATF2 axis to modulate macrophage functions., PMID:39324790
6.Intercellular Adhesion Molecule 1 (ICAM-1): An Inflammatory Regulator with Potential Implications in Ferroptosis and Parkinson's Disease., PMID:39329738
7.Targeting ICAM1 to Ameliorate Vaso-Occlusion and Inflammation in Sickle Cell Disease., PMID:39354752