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| 产地 | France |
| 品牌 | AntibodySystem |
| 货号 | YMC15801 |
| 用途 | 仅用于科研 |
| 包装规格 | 100 μg |
| 纯度 | 0.95% |
| CAS编号 | |
| 是否进口 | 否 |
| 货号 | YMC15801 |
| 产品名称 | Recombinant Mouse IL6 Protein, C-His |
| 规格 | 100 μg |
| 价格 | 1880 |
| 状态 | Lyophilized |
| 储存缓冲液 | Lyophilized from a solution in 50mM HAc, pH 3.0, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒水平 | Please contact with the lab for this information. |
| 表达系统 | E. coli |
| Accession | P08505 |
| 蛋白长度 | Phe25-Thr211 |
| 预测分子量 | 22.84 kDa |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 别名 | Hybridoma growth factor, BSF-2, IFN-beta-2, CDF, IL6, Interleukin-6, IL-6, B-cell stimulatory factor 2, Interferon beta-2, IFNB2, CTL differentiation factor |
| 物种 | Mus musculus (Mouse) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
IL6(白介素 6)属于多功能细胞因子,可激活胞内信号通路,参与免疫应答、组织重塑与物质代谢管控。多种细胞均可分泌该蛋白,表达失衡易打破机体稳态,是免疫应答、组织重塑相关研究常用靶点。
常见问题(FAQs):
Q1:这款重组小鼠IL6蛋白的纯度如何?
A:纯度大于90%,经SDS-PAGE验证,适用于ELISA、免疫原制备、Western Blot等实验。
Q2:该蛋白的表达系统和标签是什么?
A:该蛋白在大肠杆菌(E. coli)中表达,C端带有His标签(C-His),便于纯化和检测。
Q3:蛋白的生物活性是否经过验证?
A:目前生物活性测试正在进行中,该蛋白已验证可用于ELISA、免疫原、SDS-PAGE和WB等应用。
Q4:如何正确储存和复溶该蛋白?
A:蛋白为冻干粉形式,建议使用无菌水复溶。短期频繁使用可置于2-8°C保存,长期储存建议置于-20至-80°C,避免反复冻融。
前沿相关研究:
1.Salivary Interleukin-6 and Interleukin-18 Levels and Their Association with Dental Health in Children with Idiopathic Nephrotic Syndrome., PMID:40243946
2.Human IL-6-Producing B Cells Promote the Differentiation of Monocytes Toward an Anti-Inflammatory CD16⁺CD163⁺CD206⁺PD-L1⁺ Phenotype in Tuberculosis., PMID:40252014
3.Role of IL-2, IL-6, and TNF-α as Potential Biomarkers in Ischemic Heart Disease: A Comparative Study of Patients with CAD and Non-CAD., PMID:40265387
4.Investigating the relationship between the IL-17 rs2275913, IL-17 rs763780, and the IL-6 rs1800795 genotypes in HIV-positive patients with COVID-19., PMID:40268781
5.The interplay between cell-free DNA, hepcidin, and interleukin-6 in chronic kidney disease induced inflammation and progression to a hemodialysis dependent state., PMID:40272917
6.LoC-SERS detection platform based on targeted signal anchoring mechanism, high-sensitivity detection of protein biomarkers in precancerous lesions of gastric cancer., PMID:40280078