货号	YHC01001
产品名称	Recombinant Human Alpha-1-microglobulin/α1-MG Protein, N-His
规格	100 μg
价格	1880
状态	Lyophilized
储存缓冲液	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
纯度	>90% as determined by SDS-PAGE.
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
内毒水平	Please contact with the lab for this information.
表达系统	E. coli
Accession	P02760
蛋白长度	Val22-Val203
预测分子量	23.00 kDa
稳定性与储存条件	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重悬	Reconstitute in sterile water for a stock solution.
别名	AMBP, HCP, Complex-forming glycoprotein heterogeneous in charge, ITIL, Bikunin, Protein HC, EDC1, HI-30, Uronic-acid-rich protein, Protein AMBP, ITI-LC, Alpha-1 microglycoprotein, α1-MG
物种	Homo sapiens (Human)
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
备注	For research use only.

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背景介绍：

Alpha-1-microglobulin（α1-MG，α1微球蛋白）是血浆分泌型糖蛋白，具备抗氧化、免疫调控作用，参与小分子物质转运，主要由肝脏合成。表达异常可反映机体代谢状态，是机体氧化稳态、体液物质代谢方向常用研究靶点。

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前沿相关研究：

1.Urinary α 1-microglobulin and β 2-microglobulin as markers of early kidney injury in HIV-positive male patients on tenofovir-based antiretroviral therapy., PMID:38885284

2.Development of a prognostic risk model for colorectal cancer and association of the prognostic model with cancer stem cell and immune cell infiltration., PMID:40115909

3.A comparative urinary proteomic and metabolomic analysis between renal aa amyloidosis and membranous nephropathy with clinicopathologic correlations., PMID:38154551

4.Association of major candidate protein biomarkers and long-term diabetic kidney disease progression among Asians with young-onset type 2 diabetes mellitus., PMID:39142520

5.Japanese Study of the Effects of AMG (α1-Microglobulin) Reduction Rates on Survival (JAMREDS): A Protocol of a Multicenter Prospective Observational Cohort Study., PMID:38310867

6.Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial., PMID:37915963

7.Major endothelial damage markers identified from hemadsorption filters derived from treated patients with septic shock - endoplasmic reticulum stress and bikunin may play a role., PMID:38698864

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AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
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