货号	YHB98501
产品名称	Recombinant Human APOA1 Protein, N-His
规格	100 μg
价格	1880
状态	Lyophilized
储存缓冲液	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
纯度	>90% as determined by SDS-PAGE.
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
内毒水平	Please contact with the lab for this information.
表达系统	E. coli
Accession	P02647
蛋白长度	Arg19-Gln267
预测分子量	31.27 kDa
稳定性与储存条件	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
别名	ApoA-I, ProapoA-I, Apolipoprotein A1, Apo-AI, Apolipoprotein A-I, APOA1, Apolipoprotein A-I(1-242)
物种	Homo sapiens (Human)
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
备注	For research use only.

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背景介绍：

APOA1（载脂蛋白 A1）是脂质转运核心蛋白，介导外周胆固醇逆向转运，维护脂质稳态、保护内皮，主要由肝脏与小肠合成。表达紊乱易造成脂质代谢失衡，是脂代谢调控、脉管稳态研究常用靶点。

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常见问题（FAQs）：

Q1：APOA1 重组蛋白制备规格？
A：大肠杆菌表达、N‑His 标签，分子量 31.27 kDa，SDS‑PAGE 纯度＞90%。
Q2：冻干蛋白复溶方式？
A：无菌纯水调配储备液，详细操作参照配套数据表。
Q3：储存方案与保质期？
A：频繁使用 2~8℃存放，长期‑20~‑80℃保存，有效期 12 个月，防止反复冻融。
Q4：应用场景与使用要求？
A：可做 WB、ELISA、免疫原制备，活性处于验证阶段，仅用于科研

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前沿相关研究：

1.Apolipoprotein and sphingolipid measurements: Can be used in the clinical practice of atrial fibrillation diagnosing and evaluating the cryoablation effectiveness?, PMID:40036186

2.The Relationship Between Serum SFRP5, ApoA-I, HDL3-C Level and In-Stent Restenosis After PCI in Acute Myocardial Infarction and the Combined Predictive Value., PMID:40056066

3.Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity., PMID:40438591

4.Identification of Potential Functional Modules and Diagnostic Genes for Crohn's Disease Based on Weighted Gene Co-expression Network Analysis and LASSO Algorithm., PMID:40181741

5.Potential of CETP inhibition in treating dyslipidemia in systemic lupus erythematosus: Novel and comprehensive evidence from clinical studies and Mendelian randomization., PMID:40315629

6.Induction of SOX17 with stimulation of WNT, TGF-beta, and FGF signaling drives embryonal carcinomas into the yolk-sac tumor lineage resulting in increased cisplatin resistance., PMID:40025812

7.Correlation of glycosylated apolipoprotein A1 and glycosylated low-density lipoprotein cholesterol levels with glucose homeostasis and the risk of developing type 2 diabetes mellitus., PMID:40185244

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AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
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【应用领域】 目前，旗下产品已全面覆盖热门病毒与超级细菌、寄生虫、tumor相关研究、认知衰退类神经退行性疾病（阿尔茨海默症）、神经组织衰老与神经元功能紊乱相关模型、变态反应与超敏应答、免疫负调控与免疫激活等多个关键科研领域。
【产品优势】 高纯度、高特异性、高灵敏度重组蛋白、抗体以及ELISA 试剂盒。覆盖HRP、Biotin、FITC、PE、APC、PerCP等多种标记类型；适用于Human、Mouse、Rat、Rabbit、Goat等多个种属。 经WB、ELISA、IHC、IF、IP、FCM等多种实验验证，具有优异的特异性、灵敏度和批间一致性。产品常备现货，支持快速交付，并提供详实验证数据及高分文献支持，为tumor相关研究、免疫学、细胞生物学及药物研发提供可靠研究工具。
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