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| 产地 | France |
| 品牌 | AntibodySystem |
| 货号 | YHB89201 |
| 用途 | 仅用于科研 |
| 包装规格 | 100 μg |
| 纯度 | 0.95% |
| CAS编号 | |
| 是否进口 | 否 |
| 货号 | YHB89201 |
| 产品名称 | Recombinant Human OAS1 Protein, N-GST |
| 规格 | 100 μg |
| 价格 | 1880 |
| 状态 | Lyophilized |
| 储存缓冲液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒水平 | Please contact with the lab for this information. |
| 表达系统 | E. coli |
| Accession | P00973 |
| 蛋白长度 | Ser74-Pro165 |
| 预测分子量 | 37.21 kDa |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution. |
| 别名 | E18/E16, (2-5')oligo(A) synthase 1, 2-5A synthase 1, 2'-5'-oligoadenylate synthase 1, OAS1, OIAS, p46/p42 OAS |
| 物种 | Homo sapiens (Human) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
OAS1(2'-5'-寡腺苷酸合成酶1)是抵御外源侵染的关键蛋白,受干扰素诱导激活,启动内源防护机制,广泛存在于人体各类细胞。蛋白表达失衡会削弱机体防御能力,是机体抵御侵染、细胞防卫研究常用靶点。
前沿相关研究:
1.A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
2.Identification and RT-qPCR Validation of Biomarkers Based on Butyrate Metabolism-Related Genes to Predict Recurrent Miscarriage., PMID:39372587
3.Modulation of the Gut-Lung Axis by Water Kefir and Kefiran and Their Impact on Toll-like Receptor 3-Mediated Respiratory Immunity., PMID:39595633
4.Uncovering cell-type-specific immunomodulatory variants and molecular phenotypes in COVID-19 using structurally resolved protein networks., PMID:39504244
5.METTL3 depletion blocks vesicular stomatitis virus replication in pancreatic cancer cells through the establishment of an intrinsic antiviral state., PMID:40214229
6.Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689