抗TGF-β1多克隆抗体 · 兔源 · 抗原亲和纯化
| 序号 | 您的研究方向 / 需求 | 本产品可直接应用 |
|---|---|---|
| 1 | TGF-β1蛋白表达水平的定量检测 | 已验证ELISA应用,推荐稀释比1:4000-1:8000 |
| 2 | 组织切片中TGF-β1的定位与分布分析 | 已验证IHC应用,推荐稀释比1:50-1:200 |
| 3 | 细胞中TGF-β1的免疫荧光定位 | 已验证IF应用,推荐稀释比1:50-1:100 |
| 4 | 细胞裂解液中TGF-β1的蛋白免疫印迹检测 | 已验证WB应用,推荐稀释比1:1000-1:4000 |
转化生长因子-β1(Transforming Growth Factor-beta 1, TGF-β1) 是TGF-β超家族的重要成员,是一种 多功能细胞因子,在 细胞增殖、分化、迁移、凋亡、细胞外基质重塑和免疫调节 等过程中发挥关键作用。TGF-β1以 前体蛋白(proprotein) 形式合成,经蛋白酶切割后成为具有活性的成熟二聚体。
TGF-β1是 肿瘤微环境 中的核心调控因子,在多种肿瘤中高表达,通过 促进上皮-间质转化(EMT)、诱导免疫抑制、促进血管生成 等机制驱动肿瘤进展和转移。TGF-β1也是 纤维化疾病 的关键驱动因子,在肝、肺、肾纤维化中发挥重要作用。
Anti-TGFB1/TGF-beta-1 Polyclonal Antibody 是一种兔源多克隆抗体,可识别人、小鼠、大鼠的TGF-β1蛋白,已广泛应用于ELISA、IHC、IF和WB检测,是免疫学、肿瘤学和纤维化研究的 高质量工具抗体。

Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with TGFB1/TGF-beta-1 antibody (PHB91601) at 1 μg/ml.
1. Claudin18.2-positive gastric cancer-specific changes in neoadjuvant chemotherapy-driven immunosuppressive tumor microenvironment. PMID: 40128286
2. Bioinformatics-Guided Identification and Quantification of Biomarkers of Crotalus atrox Envenoming and Its Neutralization by Antivenom. PMID: 40147718
3. Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion. PMID: 40316076
4. [Expression of prophybrotic markers TGF-1, MMP-9 and FGFR in the kidneys of patients with urolithiasis during the development of chronic kidney disease]. PMID: 40377546
5. FACS-Proteomics strategy toward extracellular vesicles single-phenotype characterization in biological fluids: exploring the role of leukocyte-derived EVs in multiple sclerosis. PMID: 40394633
| Catalog No. | Product Name |
|---|---|
| PHB91601 | Anti-TGFB1/TGF-beta-1 Polyclonal Antibody |