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| 产地 | France |
| 品牌 | AntibodySystem |
| 货号 | YHC33301 |
| 用途 | 仅用于科研 |
| 包装规格 | 100 μg |
| 纯度 | 0.95% |
| CAS编号 | |
| 是否进口 | 否 |
| 货号 | YHC33301 |
| 产品名称 | Recombinant Human CD41/ITGA2B Protein, N-His |
| 规格 | 100 μg |
| 价格 | 1880 |
| 状态 | Lyophilized |
| 储存缓冲液 | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 内毒水平 | Please contact with the lab for this information. |
| 表达系统 | E. coli |
| Accession | P08514 |
| 蛋白长度 | Ala678-Leu894 |
| 预测分子量 | 26.23 kDa |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 别名 | CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb |
| 物种 | Homo sapiens (Human) |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 备注 | For research use only. |
CD41/ITGA2B(整合素α2b)是整合素复合物亚基,可与β3亚基结合形成受体复合物,介导细胞粘附与胞间信号交流。广泛表达于造血谱系细胞,功能异常会影响细胞聚集行为,是细胞粘附及造血相关机制研究的重要靶点。
前沿相关研究:
1.Spatiotemporal expression profiles of c-Mpl mRNA in the tooth germ: Comparative expression dynamics of vascularization-related genes., PMID:38336176
2.Platelet Proteome Reveals Novel Targets for Hypercoagulation in Pseudoexfoliation Syndrome., PMID:38338682
3.Extracellular vesicles are a late marker of inflammation, hypercoagulability and COVID-19 severity., PMID:38341321
4.A New δ-Globin Gene Variant: Hb A2-Yulin [δ46(CD5)Gly→Arg,HBD: C.139G > A]., PMID:38450437
5.Adjuvant effects of β-defensin on DNA vaccine OmpC against edwardsiellosis in flounder (Paralichthys olivaceus)., PMID:38471627
6.Inducible IL-2 production and IL-2+ cell expansion are landmark events for T-cell activation of teleost., PMID:38499218
7.[Effects of Platelet-Rich Plasma-Derived Exosomes on Proliferation and Migration of Tendon Stem/Progenitor Cell]., PMID:38548389
8.Improving platelet function following prophylactic platelet transfusion in patients with hematological malignancies., PMID:38682289