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| 产地 | France |
| 品牌 | AntibodySystem |
| 保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -309°C long term. |
| 货号 | RVV02824 |
| 用途 | ELISA,FCM,IF,SPR |
| 应用范围 | 一抗,中和抗体 |
| 抗原来源 | N/A |
| CAS编号 | |
| 保质期 | 1 year |
| 抗体名 | 抗 HRSV F/Fusion glycoprotein F0 纳米抗体 (SAA1194) |
| 是否单克隆 | 是 |
| 克隆性 | |
| 靶点 | F/Fusion glycoprotein F0 |
| 适应物种 | Human respiratory syncytial virus A (strain A2) |
| 形态 | Liquid |
| 宿主 | XtenCHO expression |
| 标记物 | Unconjugate,cys-tag,ready to conjugate |
| 包装规格 | 100 μg |
| 亚型 | VHH,Nanobody |
| 标识物 | Unconjugate |
| 浓度 | 1 mg/ml% |
| 免疫原 | N/A |
| 是否进口 | 是 |
| 产品货号 | RVV02824 |
| 产品名称 | Anti-HRSV F/Fusion glycoprotein F0 Nanobody (SAA1194) |
| 规格 | 100 μg |
| 价格 | 2300 |
| 宿主 | Alpaca |
| 亚型 | VHH-8His-Cys-tag |
| 种属反应性 | Human respiratory syncytial virus A (strain A2) |
| 状态 | Liquid |
| 储存缓冲液 | 0.01M PBS, pH 7.4. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 克隆类型 | Monoclonal |
| 应用实验 | ELISA, FCM, IF, SPR |
| 靶点 | Fusion glycoprotein F0, Fusion glycoprotein F2, F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1, F1, F |
| 纯化方式 | Purified by Nickel column. |
| 内毒素水平 | Please contact with the lab for this information. |
| Accession号 | P03420 |
| 稳定性与储存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 克隆号 | SAA1194 |
| 备注 | For research use only. |
背景介绍：
HRSV融合糖蛋白F0是呼吸-道合胞病毒介导膜融合的关键表面蛋白。HRSV F/Fusion glycoprotein F0纳米抗体可特异性识别F0抗原，分子量小、稳定性好，适用于病毒检测、抗原结构研究及抗-病毒相关机制探索。
前沿相关研究：
Dissociation of the respiratory syncytial virus F protein-specific human IgG, IgA and IgM response., PMID:33574352
Membrane-associated respiratory syncytial virus F protein expressed from a human rhinovirus type 14 vector is immunogenic., PMID:11277694
Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection., PMID:29029312
Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage., PMID:1375280
Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization., PMID:2251875
AntibodySystem于2019年创立于法国，专注于生命科学研究领域蛋白、抗体及试剂盒的研发与生产。致力于为 生命科学基础研究者提供高质量的科研试剂产品。
【核心产品线】 核心产品囊括：病毒/细菌相关抗体&蛋白、In Vivo功能性抗体、低背景流式抗体、高特异性纳米抗体、活性蛋白、PK/ADA试剂盒、特色小分子抗体、DNA/RNA抗体、传统多抗、经典内参及标签抗体。
【应用领域】 目前，旗下产品已全面覆盖热门病毒与超级细菌、寄生虫、tumor相关研究、认知衰退类神经退行性疾病（阿尔茨海默症）、神经组织衰老与神经元功能紊乱相关模型、变态反应与超敏应答、免疫负调控与免疫激活等多个关键科研领域。
