一、中文名称:
Anti-Human CD59 Antibody (TS59), PE (FHD02512),抗人 CD59 抗体(TS59),藻红蛋白(PE)标记,精品蛋白抗体试剂盒
二、产品描述
CD59是一种19 ~ 25 kD的糖基化磷脂酰肌醇(GPI)锚定糖蛋白,也称为保护蛋白、MACIF和H19。广泛表达于造血细胞和非造血细胞。CD59通过与C9结合、抑制C5b-8的掺入以及阻止膜攻击复合物的补体聚合的末端步骤来抑制补体的细胞溶解活性。CD59也被报道在T细胞活化中起作用。
三、产品详情
名称:体内中和抗体,活性抗体
货号:FHD02512
种属反应性:Human
宿主:Mouse
同种型:IgG1, kappa
克隆类型:Monoclonal
偶联物:PE
靶标:MSK21, MAC-inhibitory protein, MEM43 antigen, MAC-IP, MIN2, MIRL, HRF20, Protectin, 1F5 antigen, MIC11, MIN3, Membrane inhibitor of reactive lysis, MACIF, 20 kDa homologous restriction factor, CD59, MIN1, CD59 glycoprotein, HRF-20, Membrane attack complex inhibition factor
浓度:0.5 mg/ml
内毒素水平:Please contact with the lab for this information.
克隆号:TS59
应用:FCM
状态:Liquid
保存溶液:0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
稳定性和存储:Store at 4°C for 12 months. Protect from light. Do not freeze.
四、参考文献:
CD59: a promising target for tumor immunotherapy.PMID:29521526
Congenital CD59 Deficiency.PMID:26043388
Dynamics and Molecular Interactions of GPI-Anchored CD59.PMID:37505699
Cd59 and inflammation regulate Schwann cell development.PMID:35748863
Structural basis for membrane attack complex inhibition by CD59.PMID:36797260
Alternative roles for CD59.PMID:16884774
Unveiling CD59-Antibody Interactions to Design Paratope-Mimicking Peptides for Complement Modulation.PMID:37239905
Inherited CD59 deficiency, where neurology and genetics intertwine.PMID:37045466
Relating GPI-Anchored Ly6 Proteins uPAR and CD59 to Viral Infection.PMID:31739586
CD59 Expression in Skeletal Muscles and Its Role in Myasthenia Gravis.PMID:36396448
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
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