一、中文名称:
Anti-Human CD233/SLC4A1 Antibody (C4201) (FHB99810),抗人 CD233/SLC4A1 抗体(C4201),精品蛋白抗体试剂盒
二、产品描述
CD233/SLC4A1该基因编码的蛋白质是阴离子交换子(AE)家族的一部分,并在红细胞质膜中表达,其中CD233/SLC4A1起到氯化物/碳酸氢盐交换器的作用,所述氯化物/碳酸氢盐交换器参与从组织到肺的二氧化碳运输。蛋白质包含两个结构和功能上不同的结构域。N端40kDa结构域位于细胞质中,通过结合锚蛋白作为红细胞骨架的附着位点糖基化C端膜相关结构域包含12-14个跨膜段,对阴离子进行二苯乙烯二磺酸敏感的交换传递膜域C端的胞质尾与碳酸酐酶II结合编码的蛋白质与红细胞膜蛋白糖蛋白a相结合,这种结合促进了交换器的正确折叠和移位。
三、产品详情
名称:体内中和抗体,活性抗体
货号:FHB99810
种属反应性:Human
宿主:Mouse
同种型:IgG1, kappa
克隆类型:Monoclonal
偶联物:Unconjugated
靶标:Anion exchange protein 1, Anion exchanger 1, EPB3, CD233, Band 3 anion transport protein, AE 1, DI, AE1, SLC4A1, Solute carrier family 4 member 1
浓度:1 mg/ml
内毒素水平:Please contact with the lab for this information.
纯度:>95% as determined by SDS - PAGE.
纯化方式:Protein A/G purified from cell culture supernatant.
Accession号:P02730
克隆号:C4201
应用:FCM
状态:Liquid
保存溶液:0.01M PBS, pH 7.4.
稳定性和存储:Use a manual defrost freezer and avoid repeated freeze - thaw cycles. Store at 4°C short term (1 - 2 weeks). Store at -20°C 12 months. Store at -80°C long term.
四、参考文献:
Clinical Diagnosis of Red Cell Membrane Disorders: Comparison of Osmotic Gradient Ektacytometry and Eosin Maleimide (EMA) Fluorescence Test for Red Cell Band 3 (AE1, SLC4A1) Content for Clinical Diagnosis. PMID: 32636758
Identification of a cross-reacting, monoclonal anti-human CD233 antibody for identification and sorting of rhesus macaque erythrocytes. PMID: 22170815
Differential effect of plasma or erythrocyte AGE-ligands of RAGE on expression of transcripts for receptor isoforms. PMID: 19815443
详情请咨询Antibodysystem中国授权总代理-武汉佰乐博生物技术有限公司
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