佰乐博生物代理AntibodySystem，InVivoMAb Anti-Rat CD198/CCR8 Antibody (Iv0256)体内中和抗体，活性抗体
链接：https://www.antibodysystem.com/product/21632.html
名称：InVivoMAb Anti-Rat CD198/CCR8 Antibody (Iv0256)体内中和抗体，活性抗体
别名：C-C motif chemokine receptor 8, Ccr8
货号：VRE85601
宿主：Mouse
适用物种：Rat
存储缓冲区：0.01M PBS, pH 7.4.
形式：Liquid
纯度：>95%
克隆：Monoclonal
同型：IgG2a, kappa
应用：ELISA, Neutralization
内毒素水平：Please contact with the lab for this information.
UniProt：D4ADE0
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
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选购商城：https://www.antibodysystem.com
微信公众平台：佰乐博生物Biolab Reagents
参考文献：
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory. PMID: 35140181
Chemokine Receptor-Targeted Therapies: Special Case for CCR8. PMID: 35158783
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody. PMID: 36352891
S-531011, a Novel Anti-Human CCR8 Antibody, Induces Potent Antitumor Responses through Depletion of Tumor-Infiltrating CCR8-Expressing Regulatory T Cells. PMID: 37420296
Blocking CCL8-CCR8-Mediated Early Allograft Inflammation Improves Kidney Transplant Function. PMID: 35973731
CD4(+)CCR8(+) Tregs in ovarian cancer: a potential effector Tregs for immune regulation. PMID: 37950246
Oxamate enhances the efficacy of CAR-T therapy against glioblastoma via suppressing ectonucleotidases and CCR8 lactylation. PMID: 37770937
The impact of CCR8+ regulatory T cells on cytotoxic T cell function in human lung cancer. PMID: 35354899
TGF-beta-induced CCR8 promoted macrophage transdifferentiation into myofibroblast-like cells. PMID: 35377281
CCR8 is a new therapeutic target in cutaneous T-cell lymphomas. PMID: 35201316
Immunotherapy Targeting CCR8+ Regulatory T Cells Induces Antitumor Effects via Dramatic Changes to the Intratumor CD8+ T Cell Profile. PMID: 37350632
Cutting Edge: CCR8 Signaling Regulates IL-25- and IL-33-Responsive Skin Group 2 Innate Lymphoid Cell Migration and Function. PMID: 37921466
C(8)Mab-3: An Anti-Mouse CCR8 Monoclonal Antibody for Immunocytochemistry. PMID: 35377236
CCR8 Signaling via CCL1 Regulates Responses of Intestinal IFN-gamma Producing Innate Lymphoid CelIs and Protects From Experimental Colitis. PMID: 33613532
CCR8 blockade primes anti-tumor immunity through intratumoral regulatory T cells destabilization in muscle-invasive bladder cancer. PMID: 32367308
Role of chemokines in the crosstalk between tumor and tumor-associated macrophages. PMID: 36173487
The Chemokine Receptor CCR8 Is a Target of Chimeric Antigen T Cells for Treating T Cell Malignancies. PMID: 35693763
