佰乐博生物代理AntibodySystem，InVivoMAb Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2)体内中和抗体，活性抗体
链接：https://www.antibodysystem.com/product/14775.html
名称：InVivoMAb Anti-Mouse CD274/PD-L1/B7-H1 Antibody (10F.9G2)体内中和抗体，活性抗体
别名：Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, Cd274, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1
货号：VMJ70102
宿主：Rat
适用物种：Mouse
存储缓冲区：0.01M PBS, pH 7.4.
形式：Liquid
纯度：>95%
克隆：Monoclonal
同型：IgG2b
应用：FCM, Neutralization
内毒素水平：Please contact with the lab for this information.
UniProt：Q9EP73
用途范围：仅用于科研
储存：Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
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微信公众平台：佰乐博生物Biolab Reagents
参考文献：
CD274 (PD-L1) negatively regulates M1 macrophage polarization in ALI/ARDS. PMID: 38440722
CD274 (PD-L1) Methylation is an Independent Predictor for Bladder Cancer Patients' Survival. PMID: 35020560
PD-L1 degradation pathway and immunotherapy for cancer. PMID: 33159034
USP22 Deubiquitinates CD274 to Suppress Anticancer Immunity. PMID: 31399419
Mevalonate improves anti-PD-1/PD-L1 efficacy by stabilizing CD274 mRNA. PMID: 37425040
PD-L1 (CD274) promoter hypomethylation predicts immunotherapy response in metastatic urothelial carcinoma. PMID: 37868689
Tumor Mutational Burden and Response Rate to PD-1 Inhibition. PMID: 29262275
Characterizing the tumor microenvironment of metastatic ovarian cancer by single-cell transcriptomics. PMID: 34038734
CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling. PMID: 27855694
PD-L1 Distribution and Perspective for Cancer Immunotherapy-Blockade, Knockdown, or Inhibition. PMID: 31507611
PD-L1 expression in human cancers and its association with clinical outcomes. PMID: 27574444
PD-L1 immunohistochemistry: Clones, cutoffs, and controversies. PMID: 35332576
PD-L1-specific T cells. PMID: 26724936
PD-L1 CAR effector cells induce self-amplifying cytotoxic effects against target cells. PMID: 35078921
PD-L1-PD-1 Pathway in the Pathophysiology of Multiple Myeloma. PMID: 32290052
B7-H1 pathway and its role in the evasion of tumor immunity. PMID: 12721664
B7-H1/PD-1 blockade therapy in urological malignancies: current status and future prospects. PMID: 26045125
The Updated Status and Future Direction of Immunotherapy Targeting B7-H1/PD-1 in Osteosarcoma. PMID: 33536783
Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis. PMID: 21730022
Therapeutic targeting of B7-H1 in breast cancer. PMID: 21870995
Mechanisms Controlling PD-L1 Expression in Cancer. PMID: 31668929
Immunology of B7-H1 and its roles in human diseases. PMID: 14686489
