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Research Grade Anti-RSV F/Fusion glycoprotein F0 (ADI-14359),AntibodySystem Laboratories

发表时间:2023-06-13

标题:Research Grade Anti-RSV F/Fusion glycoprotein F0 (ADI-14359),AntibodySystem Laboratories

货号:DVV02811

产品链接:http://www.antibodysystem.com/product/9005.html

寄主物种:Human

形式:Liquid

存储缓冲区:0.01M PBS, pH 7.4.

浓度:1 mg/ml

纯度:>95% by SDS-PAGE.

克隆性:Monoclonal

应用:Research Grade Biosimilar

储存:Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

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参考文献:

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Cleavage of the respiratory syncytial virus fusion protein is required for its surface expression: role of furin. PMID: 10930660

Prefusion F, Postfusion F, G Antibodies, and Disease Severity in Infants and Young Children With Acute Respiratory Syncytial Virus Infection. PMID: 29029312

Intracellular processing of the human respiratory syncytial virus fusion glycoprotein: amino acid substitutions affecting folding, transport and cleavage. PMID: 1375280

Fusion glycoprotein of human parainfluenza virus type 3: nucleotide sequence of the gene, direct identification of the cleavage-activation site, and comparison with other paramyxoviruses. PMID: 3012869

Membrane-associated respiratory syncytial virus F protein expressed from a human rhinovirus type 14 vector is immunogenic. PMID: 11277694

Alkaline phosphatase fusions to the respiratory syncytial virus F protein as an approach to analyze its membrane topology. PMID: 2558867

Clinical Potential of Prefusion RSV F-specific Antibodies. PMID: 29054341

A highly stable prefusion RSV F vaccine derived from structural analysis of the fusion mechanism. PMID: 26333350

Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. PMID: 24179220

Immunogenicity and protective efficacy of adenoviral and subunit RSV vaccines based on stabilized prefusion F protein in pre-clinical models. PMID: 34973849

Global Molecular Epidemiology of Respiratory Syncytial Virus from the 2017-2018 INFORM-RSV Study. PMID: 33087438

Transdermal Immunization with Microparticulate RSV-F Virus-like Particles Elicits Robust Immunity. PMID: 35455333

Two RSV Platforms for G, F, or G+F Proteins VLPs. PMID: 32824936

Phase 1 Safety and Immunogenicity Study of a Respiratory Syncytial Virus Vaccine With an Adenovirus 26 Vector Encoding Prefusion F (Ad26.RSV.preF) in Adults Aged ≥60 Years. PMID: 32320465

RSV pre-fusion F protein enhances the G protein antibody and anti-infectious responses. PMID: 36535957

Safety and Immunogenicity of the Ad26.RSV.preF Investigational Vaccine Coadministered With an Influenza Vaccine in Older Adults. PMID: 32851411

Prefusion RSV F Immunization Elicits Th2-Mediated Lung Pathology in Mice When Formulated With a Th2 (but Not a Th1/Th2-Balanced) Adjuvant Despite Complete Viral Protection. PMID: 32849580

A prefusion-stabilized RSV F subunit vaccine elicits B cell responses with greater breadth and potency than a postfusion F vaccine. PMID: 36542692

Transient opening of trimeric prefusion RSV F proteins. PMID: 31068578

A novel RSV F-Fc fusion protein vaccine reduces lung injury induced by respiratory syncytial virus infection. PMID: 30822450

Chimeric Measles Virus (MV/RSV), Having Ectodomains of Respiratory Syncytial Virus (RSV) F and G Proteins Instead of Measles Envelope Proteins, Induced Protective Antibodies against RSV. PMID: 33669275

A live single-cycle RSV vaccine expressing prefusion F protein. PMID: 36306605

Coexpression of respiratory syncytial virus (RSV) fusion (F) protein and attachment glycoprotein (G) in a vesicular stomatitis virus (VSV) vector system provides synergistic effects against RSV infection in a cotton rat model. PMID: 34702618

Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV. PMID: 29057917

Immunogenicity of RSV F DNA Vaccine in BALB/c Mice. PMID: 27688769

Adenovectors encoding RSV-F protein induce durable and mucosal immunity in macaques after two intramuscular administrations. PMID: 31885877

Modeling maternal fetal RSV F vaccine induced antibody transfer in guinea pigs. PMID: 26319066

Alternative conformations of a major antigenic site on RSV F. PMID: 31306469

Adenovector 26 encoded prefusion conformation stabilized RSV-F protein induces long-lasting Th1-biased immunity in neonatal mice. PMID: 32566260

The importance of RSV F protein conformation in VLPs in stimulation of neutralizing antibody titers in mice previously infected with RSV. PMID: 28604155

A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus (RSV) Prefusion F Protein Is More Effective than RSV for Boosting a Primary Immunization with RSV. PMID: 33115876

New therapies for acute RSV infections: where are we? PMID: 30610420

The Respiratory Syncytial Virus (RSV) G Protein Enhances the Immune Responses to the RSV F Protein in an Enveloped Virus-Like Particle Vaccine Candidate. PMID: 36602367

A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge. PMID: 28298602

Combinatorial F-G Immunogens as Nipah and Respiratory Syncytial Virus Vaccine Candidates. PMID: 34696372

A novel respiratory syncytial virus (RSV) F subunit vaccine adjuvanted with GLA-SE elicits robust protective TH1-type humoral and cellular immunity in rodent models. PMID: 25793508

Neutralizing epitopes of RSV and palivizumab resistance in Japan. PMID: 28867684

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant. PMID: 27583777

The respiratory syncytial virus (RSV) prefusion F-protein functional antibody repertoire in adult healthy donors. PMID: 33998144

An Optimized FI-RSV Vaccine Effectively Protects Cotton Rats and BALB/c Mice without Causing Enhanced Respiratory Disease. PMID: 36298640

Attenuated Human Parainfluenza Virus Type 1 Expressing the Respiratory Syncytial Virus (RSV) Fusion (F) Glycoprotein from an Added Gene: Effects of Prefusion Stabilization and Packaging of RSV F. PMID: 28835504

Improved epitope resolution of the prefusion trimer-specific antibody AM14 bound to the RSV F glycoprotein. PMID: 34420474

In Vitro Evaluation of Glycoengineered RSV-F in the Human Artificial Lymph Node Reactor. PMID: 28952549

Level of maternal respiratory syncytial virus (RSV) F antibodies in hospitalized children and correlates of protection. PMID: 34118428

Characterisation of RSV Fusion Proteins from South African Patients with RSV Disease, 2019 to 2020. PMID: 36366419

A human antibody potently neutralizes RSV by targeting the conserved hydrophobic region of prefusion F. PMID: 36853487

Novel antigens for RSV vaccines. PMID: 26070108

Discovery and Characterization of Phage Display-Derived Human Monoclonal Antibodies against RSV F Glycoprotein. PMID: 27258388

Enhanced immunogenicity of a respiratory syncytial virus (RSV) F subunit vaccine formulated with the adjuvant GLA-SE in cynomolgus macaques. PMID: 26206269

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. PMID: 21586636

Pre-fusion F is absent on the surface of formalin-inactivated respiratory syncytial virus. PMID: 27682426

The RSV F and G glycoproteins interact to form a complex on the surface of infected cells. PMID: 18036342

Enhancing Anti-G Antibody Induction by a Live Single-Cycle Prefusion F-Expressing RSV Vaccine Improves In Vitro and In Vivo Efficacy. PMID: 36366572

RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models. PMID: 36992257

Immunogenic properties of RSV-B1 fusion (F) protein gene-encoding recombinant adenoviruses. PMID: 19622401

Protection of calves by a prefusion-stabilized bovine RSV F vaccine. PMID: 29021918

Comparison of Immune Responses to Different Versions of VLP Associated Stabilized RSV Pre-Fusion F Protein. PMID: 30769923

Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor. PMID: 31951396

RSV entry inhibitors block F-protein mediated fusion with model membranes. PMID: 12076763

Respiratory syncytial virus (RSV) F, G, M2 (22K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived. PMID: 1995956

A DNA Vaccine in Which the RSV-F Ectodomain Is Covalently Linked to the Burkholderia pseudomallei Antigens TssM and Hcp1 Augments the Humoral and Cytotoxic Response in Mice. PMID: 31681300

Detailed Evolutionary Analyses of the F Gene in the Respiratory Syncytial Virus Subgroup A. PMID: 34960794

Respiratory syncytial virus entry inhibitors targeting the F protein. PMID: 23325327

Genetic stability of RSV-F expression and the restricted growth phenotype of a live attenuated PIV3 vectored RSV vaccine candidate (MEDI-534) following restrictive growth in human lung cells. PMID: 23623857

Antibody Epitopes of Pneumovirus Fusion Proteins. PMID: 31849961

Strategic priorities for respiratory syncytial virus (RSV) vaccine development. PMID: 23598484

Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization. PMID: 2251875

Comparison of Palivizumab-Like Antibody Binding to Different Conformations of the RSV F Protein in RSV-Infected Adult Hematopoietic Cell Transplant Recipients. PMID: 29365155

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles. PMID: 23951084

Respiratory syncytial virus prefusogenic fusion (F) protein nanoparticle vaccine: Structure, antigenic profile, immunogenicity, and protection. PMID: 31416644

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